Details of the Drug

General Information of Drug (ID: DMGXCY9)

Drug Name

Calcium phosphate

Synonyms

Bonarka; Calcigenol simple; Calcium orthophosphate; Calcium phosphate; Calcium phosphate (3:2); Calcium phosphate (Ca3(PO4)2); Calcium phosphate tribasic; Calcium tertiary phosphate; Natural whitlockite; Phosphoric acid, calcium salt; Phosphoric acid, calcium salt (2:3); Synthos; TRICALCIUM PHOSPHATE; Tertiary calcium phosphate; Tribasic calcium phosphate; Tricalcium diphosphate; Tricalcium orthophosphate; beta-TCP; beta-Tricalcium phosphate

Indication

Disease Entry	ICD 11	Status	REF
Osteoporosis	FB83.0	Phase 2	[1]

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski):
0

Molecular Weight

310.174

Topological Polar Surface Area

Not Available

Rotatable Bond Count

0

Hydrogen Bond Donor Count

0

Hydrogen Bond Acceptor Count

8

Chemical Identifiers

Formula: Ca3O8P2
IUPAC Name: tricalcium;diphosphate
Canonical SMILES: [O-]P(=O)([O-])[O-].[O-]P(=O)([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
InChI: InChI=1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6
InChIKey: QORWJWZARLRLPR-UHFFFAOYSA-H

Cross-matching ID

PubChem CID: 24456
ChEBI ID: ChEBI:9679
CAS Number: 7758-87-410103-46-5
DrugBank ID: DB11348
VARIDT ID: DR00339

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Sodium-dependent phosphate transport protein 2A (SLC34A1)	DT42EWA	NPT2A_HUMAN	Substrate	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00074711) Adding Phosphorus to Osteoporosis Drug Treatment
2	Phosphate transporters and their function. Annu Rev Physiol. 2013;75:535-50.